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inducing apoptosis
AA92593 was used at 10 µM final concentration in various in vitro assays
prevents glomerular sclerosis in a Thy1 nephritis model
2) and antagonized the dopamine induction of [(35)S]GTPgammaS binding (pA2=9
Delamanid (OPC-67683) - CAS# 681492-22-8 60233 inducing apoptosisDelamanid (OPC 67683), CAS No. 681492 22 8, also known as OPC 67683, is a drug for the treatment of multi drug resistant tuberculosis. It works by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall. The drug is approved in the EU. Delamanid inhibits the synthesis of mycolic acids, crucial component of the cell wall of the Mycobacterium tuberculosis complex.
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