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PCC (25/50 U/kg) or aPCC (50/100 U/kg)
A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours
such as periodontitis
with IC(50) values well above concentrations anticipated to be achieved in vivo
PAP-1 ethylcarbamazine citrate PCC (25/50 U/kg) or aPCCSPS 4251, also known as AS 77 and PAP 1, is a KCNA3 (Potassium voltage gated channel, shaker related subfamily, member 3) channel blocker potentially for the treatment of plaque psoriasis. Kv1. 3 channels regulate the activation proliferation of effector memory T cells and thus play a critical role in the pathogenesis of autoimmune diseases. PAP 1 reduced the secretion of TNF by adipose tissue but had no effect on the secretion of IL 6. PAP 1 can also
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